Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| ESCA | rs79767741 | chr21:46247372 | C/T | 3.25E-5 | 139 | 6.5 | 7.53 | 2.63 | KM Plot |
| ESCA | rs8127770 | chr21:46255298 | C/A | 2.89E-5 | 140 | 6.77 | 7.53 | 2.63 | KM Plot |
| ESCA | rs8133972 | chr21:46249983 | C/A | 3.25E-5 | 139 | 6.5 | 7.53 | 2.63 | KM Plot |
| GBM | rs1028311 | chr6:27532950 | A/G | 6.73E-7 | 149 | 0.93 | 13.13 | 11.1 | KM Plot |
| GBM | rs10475111 | chr5:1827044 | T/C | 1.41E-5 | 148 | 11.28 | 9.8 | 0.97 | KM Plot |
| GBM | rs10654996 | chr16:67446371 | C/CTG | 8.86E-8 | 147 | 12 | 9.8 | 0.97 | KM Plot |
| GBM | rs106968 | chr1:7974544 | C/G | 9.53E-6 | 147 | 11.9 | 7.47 | 1.1 | KM Plot |
| GBM | rs10754768 | chr1:242765042 | C/T | 7.14E-7 | 144 | 1.92 | 11.17 | 11.43 | KM Plot |
| GBM | rs10803061 | chr1:242764969 | T/C | 7.14E-7 | 144 | 1.92 | 11.17 | 11.43 | KM Plot |
| GBM | rs10812492 | chr9:26909065 | G/A | 8.79E-8 | 144 | 11.4 | 12.8 | 1.23 | KM Plot |
| GBM | rs10967549 | chr9:26825738 | C/T | 5.9E-5 | 149 | 1.9 | 9.8 | 11.95 | KM Plot |
| GBM | rs10967594 | chr9:26910951 | G/T | 5.34E-10 | 149 | 11.1 | 13.52 | 1.68 | KM Plot |
| GBM | rs1105038 | chr6:73634536 | C/T | 6.79E-5 | 149 | 11.43 | 10 | 1.1 | KM Plot |
| GBM | rs11128715 | chr3:14720791 | A/G | 7.11E-5 | 149 | 1.1 | 12.97 | 10.67 | KM Plot |
| GBM | rs111633114 | chr15:81879092 | A/G | 3.97E-6 | 144 | 12 | 7.73 | 0.97 | KM Plot |